Aspirin can prevent skin cancer

June 09 [Sat], 2012, 12:09
Denmark, a new study shows: take large doses of painkillers like aspirin or ibuprofen, the crowd than most people have a lower incidence of skin cancer.

The study further evidence of long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs) may really allows people to stay away from skin cancer, especially melanoma, this subtype. However, the present study and in 2008, a show that NSAIDs with melanoma without any associated large sample studies are still contradictions.

Have been identified NASAIDs will also increase the incidence of renal cell carcinoma will increase the risk of bleeding - so study pointed out the need for further tests in order to weigh the NASAIDs other than the pain of potential risks and benefits. But the new study authors noted that associated with NSAIDs and skin cancer, that this trial is still full of meaning!

The Sigrun Alba Johannesdottir, Aarhus University Hospital, said in the e-mail to Reuters Health News of NSAIDs by inhibiting a special enzyme in the inflammatory response play a role in skin cancer incidence will be observed to prevent cell death, immune system suppression, increase the invasive and tumor blood vessels to accelerate growth and other pathological phenomena, these phenomena are associated with this type of special activity increased ".

In this study, Johannesdottir and her colleagues looked up in northern Denmark 1991-2009 medical records of over 10,008 thousands of melanoma and other low-risk skin cancer. Was diagnosed with skin cancer in patients with prescription records with 10 the same age and gender of the normal comparison. Finally, they found that: 38% of normal people usually have a large number of applications with more than two kinds of NSAIDs. Based on these findings, the study concluded: these long-term use of aspirin and other NSAIDs, the crowd than the average person has a lower incidence of skin cancer. Melanoma compared to 13% reduction in skin squamous cell carcinoma compared to 15 percent lower.

The papers published in the journal Cancer confirmed: Although no significant correlation between basal cell carcinoma and whether the application of NSAIDs, but when the researchers carefully observe these pill per week for two or more times, taking time over more than seven years of NSAID application, they found that the people of the incidence of melanoma is 46% lower than the population of 35%, squamous cell carcinoma, basal cell carcinoma 17%.

U.S. Center of Disease Control and Prevention data show that in recent years: close to 60,000 people in the United States in 2008 was diagnosed with melanoma, of which nearly 9,000 died of the disease. In sharp contrast with this country each year 2 million people were diagnosed with non-melanoma skin cancer, but only 5,000 people each year die from the disease.
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