GTecig Found Smoking causes earlier menopause in some white women

June 12 [Thu], 2014, 18:29
Although the symptoms of menopause, which include hot flashes and anxiety, can be uncomfortable, the researchers note that it also comes with increased risks of coronary artery disease, osteoporosis and death from all causes.

This is why women who enter menopause prematurely - before the average age of 50 - face added risks.

Smokers with genetic variant entered menopause 9 years early

For 14 years, the ego c twist researchers followed over 400 women between the ages of 35 and 47, who took part in the Penn Ovarian Aging Study.

The team found that women who carried variations of a gene called CYP3A4*1B and who did not smoke entered menopause an average of 13.91 years after entering the study.

However, light smokers and heavy smokers entered menopause an average of 11.36 years and 5.09 years after entering the study, respectively.

So, white females with the genetic variant who heavily smoked entered menopause about 9 years earlier than women with the genetic variants who did not smoke.

There was also a statistically significant difference in women who carried a gene called CYP1B1*3 and who smoked, though the researchers note this difference was not as strong as the findings for the other genetic variant.

Scientists have given us many reasons not to smoke, but now, researchers from the University of Pennsylvania provide evidence that, in white women with specific genetic variations, smoking causes early signs of menopause - up to 9 years earlier than average.

Publishing their study in the journal Menopause, the researchers note that although prior research has shown that smoking accelerates menopause by 1-2 years, theirs is the first to suggest that genetics and smoking increases risks of early menopause.

The team did not find the same relationship ego-t starter kit between smoking, specific gene variants and earlier menopause in black women.

"It is possible that uniform relationships among white and African American women were not found due to other factors associated with race that modify the interaction between smoking and genes," says Dr. Samantha F. Butts, assistant professor of obstetrics and gynecology at Penn Medicine.

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